EFFICACY AND SAFETY OF ANTI-INFLAMMATORY TREATMENT IN ANKYLOSING SPONDYLOARTHRITIS
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Keywords

ankylosing spondylitis, axial spondyloarthritis, sacroiliitis, non-steroidal anti-inflammatory drugs

Abstract

The aim of the study was to study the clinical and laboratory efficacy and safety of etoricoxib in patients with ankylosing spondylitis (AS).
Material and methods. The study included 40 AS patients aged 18 to 55 еars who were treated in the rheumatology department of the multidisciplinary clinic of the Tashkent Medical Academy. Based on the purpose of the study, the patients were divided into two groups: group 1 - 20 patients received etoricoxib 90 mg 1 tab x 1 times after meals, group 2 - 20 patients received Diclofenac 100 mg 1 tab. x 1 times after meals for 12 weeks.
Conclusion. After 12 weeks treatment taking etoricoxib 90 mg/day. and diclofenac 100 mg/day. in 1/3 patients with AS, the activity of sacroiliitis decreased. The frequency of side effects between etoricoxib and diclofenac did not differ significantly.

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