Keywords
Abstract
Saliva is the only biological fluid with a unique set of research capabilities that provide for complete non-invasiveness, multiple and almost unlimited sampling of material. Unfortunately, the mechanism that regulates the maintenance of a certain composition of saliva is still unclear. The main attention of clinical specialists is attracted by new laboratory methods for analyzing saliva in order to obtain a variety of diagnostic information. Advances are predicted in the field of diagnosing various diseases, taking into account the properties of saliva. We studied the relationship between the biochemical composition of saliva and blood plasma in normal conditions in our experimental condition, and they are given in this paper.
References
Kochurova E.V. Diagnostic possibilities of saliva. Clinical laboratory diagnostics. 2014; 1:13–6.
Khaustova S.A., Shkurnikov M.Yu., Grebenyuk E.S., Artyushenko V.G., Tonevitsky A.G. Determination of the biochemical parameters of saliva using Fourier spectroscopy of the middle infrared. Byulleten’ eksperimental’noy biologii i meditsiny. 2009; 148(11): 597-600. (in Russian).
Pereira Lima D., Garcia Diniz D., Adas S., Moimaz S. Saliva: Reflection of the body. International Journal of Infectious Diseases 2010; 14:184-8.
Chiappin S., Antonelli G., Gatti R., De Palo E.F. Saliva specimen: a new laboratory tool for diagnostic and basic investigation. Clinica Chimica Acta. 2007; 383: 30-40.
Spielmann N., Wong D.T. Saliva: diagnostics and therapeutic perspectives. oral diseases. 2011; 17: 345-54.
Zhang Y., Sun J., Lin C., Abemayor E., Wang M.B., Wong D.T. The Emerging Landscape of Salivary Diagnostics. OHDM. 2014; 13(2):200-10.
Wong D.T. Salivaomics. Journal of the American Dental Association. 2012; 143:19S-24S.
Bandhakavi S., Stone M.D., Onsongo G., Van Riper S.K., Griffin T.J. A dynamic range compression and three-dimensional peptide fractionation analysis platform expands proteome coverage and the diagnostic potential of whole saliva. J. Proteome Res. 2009; 8: 5590–600.
Loo J.A., Yan W., Ramachandran P., Wong D.T. Comparative human salivary and plasma proteomes. J. Dent.Res. 2010; 89: 1016–23.
Goswami Y., Mishra R., Agrawal A.P., Agrawal L.A. Salivary Biomarkers-A Review of Powerful Diagnostic tool. IOSR Journal of Dental and Medical Sciences. 2015; 14 (3): 80-7.
Ialongo C. Preanalytic of total antioxidant capacity assays performed in serum, plasma, urine and saliva. clinical biochemistry. 2017; 50(6): 356-63.
Riis J.L., Bryce C.I., Ha T., Hand T., Stebbins J.L., Matin M., Jaedicke K.M., Granger D.A. Adiponectin: Serum-Saliva Associations and Relations with Oral and Systemic Markers of Inflammation. Peptides. 2017; 91:58-64.
Byrne M.L., O’Brien-Simpson N.M., Reynolds E.C., Walsh K.A., Laughton K., Waloszek J.M., Woods M.J., Trinder J., Allen N.B. Acute phase protein and cytokine levels in serum and saliva: A comparison of detectable levels and correlations in a depressed and healthy adolescent sample. Brain, Behavior and Immunity. 2013; 34:164-75.
Sun Y., Liu S., Qiao Z., Shang Z., Xia Z., Niu X., Qian L., Zhang Y., Fan L., Cao C.-X., Xiao H. Systematic comparison of exosomal proteomes from human saliva and serum for the detection of lung cancer. Analytica Chimica Acta. 2017; 982: 84-95.
Fernandez-Botran R., Miller J.J., Burns V.E., Newton T.L. Correlations among inflammatory markers in plasma, saliva and oral mucosal transudate in postmenopausal women with past intimate partner violence. Brain Behavior and Immunity 2011; 25:314–21.
Williamson S., Munro C., Pickler R., Grap M.J., Elswick R.K. Comparison of biomarkers in blood and saliva in healthy adults. Nurs. Res. Pract. 2012; Article ID 246178: 4.
Cullen T., Thomas A.W., Webb R., Hughes M.G. The relationship between interleukin-6 in saliva, venous and capillary plasma, at rest and in response to exercise. Cytokine. 2015; 71(2): 397-400.
Clinical biochemistry. Collection of instructions. Novosibirsk: ZAO Vector-Best; 2011.
Ostrovsky O.V., Khramov V.A., Popova T.A. Biochemistry of the oral cavity. Volgograd: VolGMU Publishing House; 2010.
Khramov V.A., Prigoda E.V. The level of amino nitrogen and imidazole compounds in human oral fluid. Dentistry. 2002; 6: 10-1.
Romanenko E.G., Rudenko A.I. Method for the determination of sialic acid in saliva. The world of biology and medicine. 2013; 1: 139-42.
Belskaya L.V. The use of capillary electrophoresis to determine the mineral composition of human saliva. Bulletin of science and practice. 2017; 2(15): 132-40.
Korolyuk M.A., Ivanova L.I., Mayorova I.G., Tokarev V.E. Method for determining catalase activity. Laboratory work. 1988;1:16–9.
Volchegorsky I.A., Nalimov A.G., Yarovinsky B.G. Comparison of different approaches to the determination of products in heptaneisopropanol blood extracts. Questions of medical chemistry. 1989; 1: 127-31.
Gavrilov V.B., Bidula M.M., Furmanchuk D.A., Konev S.V., Aleinikova O.V. Assessment of intoxication of the organism by the imbalance between the accumulation and binding of toxins in the plasma. Clinical laboratory diagnostics. 1999; 2:13–7.
Cohen M., Khalaila R. Saliva pH as a biomarker of exam stress and a predictor of exam performance. Journal of Psychosomatic Research. 2014; 77(5): 420-5.
Ramya A.S., Uppala D., Majumdar S., Surekha Ch., Deepak K.G.K. Are salivary amylase and pH – Prognostic indicators of cancers? Journal of Oral Biology and Craniofacial Research. 2015; 5(2): 81-5.
Kaminskaya L.A. Prospects for studying the biochemical parameters of oral fluid in laboratory diagnostics. Russian stomatology. 2010; 3:36-42. (in Russian).
Rodrigues V.P., Franko M.M., Marques C.P.C., de Carvalho R.C.C., Leite S.A.M., Pereira A.L.A., Benatti B.B. Salivary levels of calcium, phosphorus, potassium, albumin and correlation with serum biomarkers in hemodialysis patients. Archives of oral biology. 2016; 62:58–63.
Mori M., Iwata T., Satori T., Ohira S-I., Itabashi H., Tanaka K. Ionexclusion/cation-exchange chromatographic determination of common inorganic ions in human saliva by using an eluent containing zwitterionic surfactant. Journal of Chromatography A. 2008; 1213: 125-9.
Shirzaiy M., Heidari F., Dalirsani Z., Dehghan J. Estimation of salivary sodium, potassium, calcium, phosphorus and urea in type II diabetic patients. Diabetes&Metabolic Syndrome: clinical research&reviews. 2015; 9 (4): 332-6.
Meyer-Lueckel H., Chatzidakis A.J., Kielbassa A.M. Effect of various calcium/phosphates ratios of carboxymethylcellulose-based saliva substitutes on mineral loss of bovine enamel in vitro. Journal of Dentistry. 2007; 35:851-7.
Tanaka T., Kobayashi T., Takii H., Kamasaka H., Ohta N., Matsuo T., Yagi N., Kuriki T. Optimization of calcium concentration of saliva with phosphoryl oligosaccharides of calcium (POs-Ca) for enamel remineralization in vitro. Archives of Oral Biology. 2013; 58: 174-80.
Borisenkov M.F., Yerunova L.A., LyusevaYe.M., Pozdeyeva N.V. Daily dynamics of the total antioxidant activity of human saliva. Physiologiya cheloveka. 2007; 33(3): 137–8. (in Russian)
Volchegorskiy I.A., Kornilova N.V., Butyugin I.A. Comparative analysis of the state of the system “lipid peroxidation – antioxidant protection” in the saliva of patients with chronic periodontitis of mild and moderate severity. Dentistry.2010; 6:24–8. (in Russian).
Kamilov R.F., Khanov T.V., Yapparov R.N., Shakirov D.F. Chemiluminescence as a method of assessing the overall antioxidant activity of blood, saliva, tear fluid and urine. Klinicheskaya laboratornaya diagnostika.2009; 2:21–2, 35–6. (in Russian).
Tartaglia G.M., Gagliano N., Zarbin L., Tolomeo G., Sforza C. Antioxidant capacity of human saliva and periodontal screening assessment in healthy adults. Archives of Oral Biology. 2017; 78:34-8.
Mobarak E.H., Abdallah D.M. Saliva nitric oxide levels in relation to caries experience and oral hygiene. Journal of Advanced Research. 2011; 2(4): 357-62.
Korde (Choudhari) Sh., Sridharan G., Gadbail A., Poornima V. Nitric oxide and oral cancer: A review. oral oncology. 2012; 48(6): 475-83.
Rocha B.S., Lundberg J.O., Radi R., Laranjinha J. Role of nitrite, urate and pepsin in the gastroprotective effects of saliva. Redox Biology. 2016; 8: 407-14.
Noskov V.B. Saliva in clinical laboratory diagnostics (literature review). Clinical laboratornaya diagnostika. 2008; 6:14-7. (in Russian).